The various effect of Maandi in various house from lagna in short is as follows.
Lagnam or first house. If Gulika alone stands in first house, that may brings Raja Yoga, however the subject may suffer from injury, burn etc in the body frequently. If Gulika is placed with other graha, he may be short lived and cruel.
Second house. His native house of birth will destroy and he will has predictive power too. He may suffer financial problems in life and may cause serious obstacles in education. He may argue for his attitude and this may bring many hostilities in life.
Third house. Lack younger siblings or death of younger siblings may happen. He may borrow money and may has hostile attitude towards siblings.
Fourth house. Cause harm to mother and house. May cause vehicle accidents in life. If there is good aspects from other good planets, effect may reduce.
Fifth House. Associated with mercury may cause mental illness or a state of mad in life. May suffer from death of son, short life span, stomach problems, mental tension etc.
Sixth House. Good for studying magic. He become a terror for thieves. He will hate blood related ones. He will win cases and arguments.
Seventh House. He will cause severe harm for the name and fame of family. He may kill his wife and accept other persons' wife in life.
Eight house. May has injury to face, short span of life, cause many illness, may cause unnatural death in life too etc.
Ninth House.Bad luck in life. He may be a non believer of God.
Tenth House. Good for charitable deeds. He will have scientific knowledge. But may suffer from serious laziness in work.
Eleventh House. Will attain material wealth in life. May separate from elder brother.
12th House. He may afraid of dead bodies and see dreams of attacks from dead ones etc. He has serious fright in night and burial place. He may be known as miser in public. He deposits money in bank for future needs.
The above are general and aspects and other planetory position etc to be considered for providing final conclusion.
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By - Nash Thomas